Gut Health & Histamine

Epigenozyme Hist-Redux incorporates bioflavonoids, micronutrients, proteolytic enzymes, and herbs into a comprehensive formula that provides multifaceted support for individuals with immune imbalances. Dihydroquercetin, a key component in Hist-Redux, inhibits oxidation, is bioactive, and is highly absorbable. Hist-Redux supports the body’s regulating function in addressing an overactive or distressed histamine response that are sometimes brought on by the environment*.

*Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Quercetin

• Potent bioflavonoid*
• Promotes healthy enzyme levels*
• Supports normal sinus and respiratory function*

Quercetin has been shown to be one of the most useful and physiologically active flavonoids.* Quercetin helps support stable mast cells to promote healthy inflammatory balance. This potent bioflavonoid can be used for maintaining or supporting the proper levels of enzymes and physiologic factors necessary for normal respiratory and sinus health, to help support seasonal respiratory challenges.*

*Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Clinical Applications

Magnesium is one of the most important minerals for human physiology, serving as a cofactor in over 300 enzymatic reactions. The 2013 NHANES found that 48% of the United States population consumed less than the recommended daily allowance for magnesium. Additionally, magnesium status can be negatively impacted by aging, certain health conditions, medications, exercise and diet choices.

A sufficient level of magnesium is essential for the health and function of the brain. Some of its most important functions are protecting the integrity of the blood brain barrier (BBB), serving as a cofactor for neurotransmitter synthesis, and modulating receptors. The transportation of magnesium into the brain is normally a restricted process due to the tight regulation of magnesium in blood.

In 2010, researchers at the Massachusetts Institute of Technology published their novel discovery of magnesium L-threonate, the only magnesium complex shown to specifically increase magnesium levels within the brain. Intraneuronal magnesium has been scientifically demonstrated to support neuroplasticity and mental focus, and improve memory in the aging brain. It promotes quality of life by supporting a balanced sleep-wake cycle and mood. Mag Threonate can also help alleviate occasional nervousness and stress.

Sleep Quality

Poor sleep affects 62% of adults worldwide. Insufficient magnesium intake and poor sleep have been correlated in several studies. Some mechanisms to explain the connection of poor sleep with inadequate magnesium are the ability of magnesium to bind gamma-aminobutyric acid (GABA) receptors, attenuation of the stress response or its role as a cofactor in melatonin synthesis.

Mental-Emotional Health

A 2023 survey reports that 49% of adults in the United States report frequent stress. Symptoms of low mood and nervousness can occur independently of stress but are often experienced at the same time. In the brain, magnesium supports mood and emotional health by acting as a cofactor for the synthesis of dopamine and serotonin, inhibiting the release of excitatory glutamate and binding calming GABA receptors.

Memory and Concentration

Memory and mental focus are common patient concerns. In an animal model, magnesium L-threonate was found to increase the synaptic density and function of neurons in the brain. A decline in neuronal synapses, their function and consequent atrophy of the brain are associated with impaired cognition, a process that increases with age. In a study of older adults with memory concerns, those that received 1.5 to 2 g of magnesium L-threonate daily demonstrated improvement in executive function, working (short-term) memory and episodic memory.

Suggested Use:

2 capsules per day or as recommended by your health care professional.

*Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Epigenozyme DPP IV digestive enzymes have been designed to support Gluten/Casein digestion* . Epigenozyme DPP IV is a one-of-a-kind digestive enzyme that is designed not only to offer DPP IV gluten-digestive enzyme, but also to support the intestines, using specifically targeted bioflavoniods to address unintentional gluten and casein exposure.* This formula is also intended to support the digestion of the prolamine rich peptides in gluten and aids the intestinal barrier.* This two in one approach means you are not only addressing digestion of reactive gluten and casein proteins, but also the downstream effects of those exposures*.

*Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.