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Epigenozyme High Poten-C is a blend of vitamin C and various flavonoid compounds to provide enhanced vitamin C support. Epigenozyme High Poten-C helps maintain a healthy immune system as well as support to blood vessel integrity and healthy cell function.

* High Poten-C contains 1730 mg per serving, which is significantly more than most vitamin C products*

*Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any diseases or health condition.

Epigenozyme's DAO-Redux formula has DiamineOxidase (DAO),an enzyme responsible for degradation of ingested histamine*. DAO has been clinically tested and found to break down food-derived histamine in the digestive tract*. DAO is not absorbed, does not have systemic activity*. DAO-Redux does not manage or address antibody-related/IgE food allergies*. Supports Degradation of Food-Derived Histamine, enhances the presence of DAO in the GI Tract*.

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health conditions.

Epigenozyme High Potency Omega-3 Fish Oil contains natural enzymatically enhanced monoglyceride fish oil that has a three times greater EPA/DHA absorption rate than an equivalent dose of ethyl ester fish oil*. Formulated to minimize digestive discomfort and decrease risk of burping up fish taste*. Support cardiovascular health*. Support anti-inflammation*. Support cognitive, brain, and eye health*.

*Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Epigenozyme Hist-Redux incorporates bioflavonoids, micronutrients, proteolytic enzymes, and herbs into a comprehensive formula that provides multifaceted support for individuals with immune imbalances. Dihydroquercetin, a key component in Hist-Redux, inhibits oxidation, is bioactive, and is highly absorbable. Hist-Redux supports the body’s regulating function in addressing an overactive or distressed histamine response that are sometimes brought on by the environment*.

*Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Phosphatidylserine is the most abundant phospholipid in the human brain and is made by the body in small amounts. This important phospholipid supports neuronal cell integrity by providing the building blocks needed for cell membrane structure and function.^† Cell membranes not only act as a barrier between the inside and outside of a cell, but also play an important role in cellular communication and normal cellular responses. Phosphatidylserine has also been documented to increase the availability of choline for synthesis of acetylcholine, an important neurotransmitter involved in memory and learning. It may also help enhance cognitive function by maintaining cholinergic activity in the brain.^†

^{The brain makes up only 2% of a person’s body weight, yet it consumes roughly 20% of the body’s energy when at rest. Many nutrients have been shown to support optimal neurologic and cognitive function. In addition to the well-known omega-3 fatty acid DHA, other nutrients have demonstrated efficacy in supporting cognitive function.} 

Phosphatidylserine

Phosphatidylserine (PS) is an endogenous phospholipid. Although it is less abundant in the body than other phospholipids (i.e., phosphatidylcholine and phosphatidylethanolamine), it still comprises 2–10% of the body’s total phospholipids, with critical functions in several biological areas, such as apoptosis (programmed cell death), blood clotting, and cell-to-cell communication.¹ The PS molecule consists of a glycerol-phosphate backbone, the alpha-amino acid serine, and two fatty acids. As with other phospholipids, PS is a critical component in the structure of membranes, particularly neurons.²

In the body, phospholipids form a variety of structures owing to their amphipathic nature, i.e., having both a hydrophobic  (“water-fearing”) non-polar tail and hydrophilic (“water-loving’) polar head. They can move within the fluid mosaic of cell membranes, which supports cellular communication, selective passage of macromolecules, and other important cellular functions. Phosphatidylserine is the most abundant negatively charged phospholipid in eukaryotic cell membranes.³ As the major acidic phospholipid in the brain, PS can traverse the blood-brain barrier after oral administration.⁴ In animal studies, it has been shown to influence several neurochemical systems, neuronal membranes, cell metabolism, and several neurotransmitters, including serotonin and dopamine.^†5-7  

Several clinical trials have shown that PS supplementation supports cognitive function.^†

Several clinical trials have shown that PS supplementation supports cognitive function.^† In one randomized, controlled clinical trial, 36 children, aged 4 to 14 years, who were experiencing attention-related issues were given 200 mg/d of PS or placebo for two months.⁸ PS supplementation resulted in significant improvements in attention, impulsive movement, and short-term auditory memory as compared with placebo. PS was well-tolerated and showed no adverse effects. 

Phosphatidylserine has further been shown to support healthy endocrine and adrenal responses to mental stress.^†  In a double-blind study, PS (400 mg, 600 mg, or 800 mg/d) was administered to healthy women and men 20 to 45 years old.⁹ In the groups receiving 400 mg/d of PS only, researchers observed a pronounced blunting of both serum ACTH and cortisol, and salivary cortisol responses to the Trier Social Stress Test (TSST). There was also a positive effect on emotional responses to the TSST at 400 mg/d. While the placebo group showed the expected increase in distress after the test, the group treated with 400 mg PS showed a decrease. The effect was not seen with larger doses. These results suggest that PS may dampen hypothalamic-pituitary-adrenal (HPA) axis stress responses.^† 

Phosphatidylserine also supports cognitive function in aging individuals.^† In a clinical trial, 70 elderly subjects with cognition complaints were randomly allocated to four groups: 17 patients received only social support, 18 patients received cognitive training twice a week, 17 patients received cognitive training combined with pyritinol 2 x 600 mg/d, and 18 patients received cognitive training combined with phosphatidylserine (200 mg BID). Researchers concluded that PS supplementation combined with cognitive training led to transient improvement of cognitive and memory function, as well as improved electrophysiological brain function.^†10 

*Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

One of the 9 essential amino acids that must be obtained from food, L-lysine is a key player in enzyme production, collagen formation, and tissue repair. L-lysine intake may be inadequate in low-protein diets.

 *Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Epigenozyme DPP IV digestive enzymes have been designed to support Gluten/Casein digestion* . Epigenozyme DPP IV is a one-of-a-kind digestive enzyme that is designed not only to offer DPP IV gluten-digestive enzyme, but also to support the intestines, using specifically targeted bioflavoniods to address unintentional gluten and casein exposure.* This formula is also intended to support the digestion of the prolamine rich peptides in gluten and aids the intestinal barrier.* This two in one approach means you are not only addressing digestion of reactive gluten and casein proteins, but also the downstream effects of those exposures*.

*Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

Epi- Omega-3 TG  provides 820 mg of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) per soft gel as natural triglycerides, the preferred form with superior absorption. Vitamin E (as mixed tocopherols) and rosemary extract are used to ensure maximum purity and freshness.

CLINICAL APPLICATIONS